Cynor Laboratories

4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide (CAS 118854-48-1) is a crucial pharmaceutical intermediate, primarily used in synthesizing non-steroidal anti-inflammatory drugs (NSAIDs), most notably Meloxicam, for treating arthritis and pain. Structurally, it features a benzothiazine ring, a sulfone group (1,1-dioxide), a hydroxyl group, and an isopropyl ester, giving it specific solubility and reactivity for drug synthesis, often appearing as a white to off-white solid, with handling requiring standard chemical precautions like gloves and ventilation. 

1-Methoxy-2,4-dimethyl-3-nitrobenzene (CAS Number: 95644-98-7) is a chemical compound with the molecular formula C₉H₁₁NO₃ and a molecular weight of 181.19 g/mol. It is also known by synonyms such as Benzene, 1-methoxy-2,4-dimethyl-3-nitro.

3,5-Dimethylpyrazole (3,5-DMP) is a white, crystalline organic solid, a derivative of pyrazole, known for its use as a versatile chemical intermediate in synthesizing pharmaceuticals, dyes, and high-performance resins, acting as a catalyst or improving material properties like thermal stability and adhesion. It's a heterocyclic compound with the formula C5H8N2cap C sub 5 cap H sub 8 cap N sub 2𝐶5𝐻8𝑁2, characterized by methyl groups at the 3 and 5 positions, offering good solubility in polar solvents and a distinct pleasant odor, with a melting point around 107-108°C. 

2-Hydroxy-3,5-dibromopyridine is a chemical compound with the molecular formula C5H3Br2NO. It is also known as 3,5-Dibromo-2-hydroxypyridine or 3,5-dibromopyridin-2-ol. It is a fine chemical, often used in laboratories. 

2-Amino-4-methylpyridine, also known as 4-Methyl-2-pyridinamine, is a chemical compound with the molecular formula C6H8N2. It appears as crystals or powder, with a white to pale yellow color. It is soluble in water, lower alcohols, chloroform, ethyl acetate, and DMF. This compound is known for its role as a potent inhibitor of inducible nitric oxide synthase (iNOS) (also known as NOS2).

N,N,N',N'-Tetramethylethylenediamine (TMEDA or TEMED) is a chemical compound, a bidentate tertiary amine, used as a catalyst in organic polymerisation, particularly in the preparation of polyacrylamide gels for electrophoresis and as a ligand for metal ions. Here's a more detailed description:

Chemical Formula: (CH3)2NCH2CH2N(CH3)2 

Structure: TMEDA is an ethylenediamine derivative where each nitrogen atom carries two methyl substituents. 

Applications:

Polymerization Catalyst: It's used with ammonium persulfate to initiate the polymerization of acrylamide and bis-acrylamide, forming polyacrylamide gels. 

Ligand for Metal Ions: TMEDA forms stable complexes with various metal ions and is a good ligand for organolithium chemistry. 

Electrophoresis: It's used in electrophoresis applications to enhance protein and nucleic acid separation. 

Organic Synthesis: Used as a reagent in various organic reactions, facilitating the formation of complex molecules. 

Properties:

Appearance: Colorless to almost colorless clear liquid. 

Solvating Properties: TMEDA is a Lewis base with good solvating properties. 

Flammability: Highly flammable liquid and vapor. 

Toxicity: Toxic if swallowed or inhaled, harmful in contact with skin, causes severe skin burns and eye damage.

Chemical Formula:
**C₆H₁₈O₂Si₂

Molecular Weight:
162.42 g/mol

CAS Number:
63148-62-9

IUPAC Name:
Hexamethyldisiloxane

Physical Properties:

• Appearance: Clear, colorless, and odorless liquid.
• Boiling Point: 100°C (212°F)
• Melting Point: -80°C (-112°F)
• Density: 0.805 g/cm³ at 20°C.
• Flash Point: < -18°C (0°F), highly flammable.
• Viscosity: 0.65 cP (centipoise) at 25°C.
• Solubility: Insoluble in water, but soluble in organic solvents like benzene, toluene, and ethanol.
• Vapor Pressure: 26 mm Hg at 20°C.

Chemical Structure:

Hexamethyldisiloxane is a member of the silicone family. It has a siloxane (Si-O) backbone, where two silicon (Si) atoms are bonded to oxygen atoms, and each silicon is bonded to three methyl groups (CH₃), making it a dimethylsiloxane compound.

Key Uses and Applications:

1. Surface Modification:

   • Hexamethyldisiloxane is widely used for surface treatments in industries like electronics and materials science. It is often applied to modify the surface of glass, metals, and ceramics to improve their hydrophobicity (water-repellent properties) and enhance their chemical resistance.

2. Silicone Oil and Polymer Synthesis:

   • It is an important precursor in the synthesis of silicone oils and polymers. The compound's structure is key in creating materials with useful properties such as flexibility, resistance to extreme temperatures, and electrical insulation.

3. Cosmetics and Personal Care:

   • In cosmetics, Hexamethyldisiloxane is used as an ingredient in skin creams, hair care products, and deodorants. It functions as an emollient, providing a silky smooth texture, while also helping to smooth and hydrate the skin.

4. Aerospace and Automotive Industries:

   • Due to its low viscosity and thermal stability, Hexamethyldisiloxane is utilized in lubricants and greases, particularly in high-performance aerospace and automotive applications.

5. Hydrophobic Coatings:

   • It plays a crucial role in creating hydrophobic coatings for a wide range of applications, including protective coatings on electronic devices, solar panels, and outdoor gear.

6. Laboratory Reagent:

   • Hexamethyldisiloxane is often used in organic synthesis as a reactive intermediate for creating silane-based compounds. It is also utilized as a molecular sieve, for chemical vapor deposition (CVD) processes, and in vacuum deposition techniques for producing thin films.

2-Chloro-5-iodobenzoic Acid, with CAS Number 19094-56-5, is a white to light yellow crystal powder that serves as a synthetic intermediate in organic chemistry for the preparation of metabotropic glutamate receptor subtype-2 (mGluR2) positive allosteric modulators and cell-permeable protein tyrosine phosphatase inhibitors. Its molecular formula is C7H4ClIO2, and it has a molecular weight of approximately 282.46 g/mol.